Starting point for designing drugs that cure clostridium difficile

A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff — a virulent health care-associated infection that causes severe diarrhea, nausea, internal bleeding, and potentially death. The bacteria affects roughly half-a-million Americans and causes nearly 15,000 deaths in the U.S. annually.advertisement Overuse of […]

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A new breakthrough in developing effective antimalarial drugs

Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites manage to acclimatize to these two completely different hosts because the plasticity of their genome enables them to adapt as necessary. Scientists at the Institut Pasteur and the CNRS decided to investigate the epigenetic mechanisms behind this […]

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Using a chip to find better cancer fighting drugs

Kyoto University researchers have developed a new ‘tumor-on-a-chip’ device that can better mimic the environment inside the body, paving the way for improved screening of potential cancer fighting drugs.advertisement The path to drug discovery is never easy. Scientists and clinicians can go through tens-of-thousands of potential compounds for years to find a handful of viable […]

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Separating drugs with MagLev

The composition of suspicious powders that may contain illicit drugs can be analyzed using a quick and simple method called magneto-Archimedes levitation (MagLev), according to a new study published in the journal Angewandte Chemie. A team of scientists at Harvard University, USA, has developed the MagLev method to differentiate common street drugs in dilute mixtures. The […]

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Scientists find promising drug combination against lethal childhood brain cancers

Researchers have devised a new plan of attack against a group of deadly childhood brain cancers collectively called diffuse midline gliomas (DMG), including diffuse intrinsic pontine glioma (DIPG), thalamic glioma and spinal cord glioma. Scientists at the National Institutes of Health, Stanford University, California, and Dana-Farber Cancer Institute, Boston, identified a drug pair that worked […]

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